Production and purification of protein nanopores for health and biotechnologies

Equipment, AAP 2019-2

Team : Laboratory for Analysis and Modelling for Biology and Environment, Team Polymères Matériaux aux Interfaces

Project leader : Benjamin Cressiot

Abstract :

Biological and hybrid nanopores are ideal candidates for single molecule sensing and for the understanding of fundamental chemical principles in nanoscale dimension. Being able to understand the transport properties under the confinement effect is critical in many fields, ranging from biological applications to energy ones. The project focuses on the purification of these protein nanopores, a model for studying protein folding involved in conformational disease, peptides of different amino-acid composition.

Themes :

• Health, Welfare, Biotechnologies and Industry

• Time  resolved  and  multi-techniques characterization

Collaborations :

• ENS Paris, Institute of Porous Materials of Paris (Christian Serre, Mathilde Lepoitevin)
• Collège de France, Chemistry of Materials and Energy (Jean-Marie Tarascon)
• C2N, Team Elphyse (Gilles Patriarche)
• Hospital Laribosière, team of Philippe Manivet